Lactate Dehydrogenase Isoenzymes


Nathaniel W. Revis, R. Y. Thomson and A. J. V. Cameron, “Lactate Dehydrogenase Isoenzymes in the Human Hypertrophic Heart”,  Cardiovascular Research, Volume 11 Issue 2, Pages 172-176, 1977


Lactate Dehydrogenase Isoenzymes in the Human Hypertrophic Heart

1. N. W. REVIS1,
2. R. Y. THOMSON and
+ Author Affiliations

1 Address for correspondence and reprints: N. W. Revis, University of Tennessee Biomedical
Graduate School, Biology Division, PO Box Y, Oak Ridge, Tennessee 37830, USA.


Lactate dehydrogenase isoenzymes have been measured in human hearts at autopsy. As compared with normal hearts, hypertrophic hearts and ischaemic hypertrophic hearts showed a shift in the isoenzyme distribution. This shift appeared to be more closely associated with an increase in the relative proportion of fibrous tissue than with changes in the myocardial cells.

Copyright © 1977, European Society of Cardiology

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